2,3,5-Trimethyl-1,4-hydroquinone

Ethyl (1R,4S,5R,9S,10R,13S)-5,9,13-trimethyl-14-methyl­ene-14-oxotetra­cyclo­[11.2.1.01,10.04,9]hexa­decane-5-carboxyl­ate

The title compound, C(22)H(34)O(3), was synthesized from isosteviol. The asymmetric unit contains of two independent mol-ecules with the same absolute configurations. In both the mol-ecules, the three six-membered rings adopt chair conformations, the stereochemistry of the A/B and B/C ring junctions are trans, and the five-membered ring D adopts an envelope conformation.

Jcb_200811138 235..250

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 185 No. 2 235–249 www.jcb.org/cgi/doi/10.1083/jcb.200811138 JCB 235 Correspondence to Claudio Sette: [email protected]; or Stéphane Richard: [email protected] Maria Paola Paronetto’s present address is Centre de Regulaciò Genomica, Barcelona 08003, Spain. Abbreviations used in this paper: ANOVA, analysis of variance; dp...

Mol081240 235..244

Ethanol levels reached in circulation during moderate-to-heavy alcohol intoxication (50–100 mM) modify Caand voltagegated K (BK) channel steady-state activity, eventually altering both physiology and behavior. Ethanol action on BK steadystate activity solely requires the channel-forming subunit slo1 within a bare lipid environment. To identify the protein regions that confer ethanol sensitivity...

Bez nazwy-235

14-Eth­oxy-4,6,9-trimethyl-8,12-dioxa-4,6-diaza­tetra­cyclo­[8.8.0.02,7.013,18]octa­deca-2(7),13,15,17-tetra­ene-3,5,11-trione

In the title compound, C(19)H(20)N(2)O(6), the pyrone and pyran rings adopt envelope conformations with the same common C atom as the flap, the dihedral angle between the planes of the remaining ring atoms being 68.27 (4)°. The planar atoms of the pyran ring and the diaza-cyclic ring are almost coplanar, the dihedral angle between their mean planes being 3.29 (7)°. Moreover, the planar atoms of...